Thanks to the BBC for bringing this to my attention. Using photo-activatable chromatophores and some clever fusions combined with computational control algorithms this group was able to partially control gene expression in S.cerevisiae yeast. Could be the start of something big.
Link to the paper:
In silico feedback for in vivo regulation of a gene expression circuit
Andreas Milias-Argeitis1, 4 Sean Summers1, 4 Jacob Stewart-Ornstein2, 4 Ignacio Zuleta2 David Pincus2 Hana El-Samad2 Mustafa Khammash3 John Lygeros1